Mycobacterium tuberculosis and Phenotypic Drugs Susceptibility Tests
نویسندگان
چکیده
منابع مشابه
Development of rifapentine susceptibility tests for Mycobacterium tuberculosis.
Two methods for testing the susceptibility of Mycobacterium tuberculosis to rifapentine have been developed: the agar proportion method and the radiometric BACTEC technique. A critical concentration of 0.5 microg of rifapentine per ml is proposed for both methods since it provides a reliable means of distinguishing between susceptible and resistant M. tuberculosis isolates. It is recommended th...
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Salicylate induces multiple antibiotic resistance in various bacterial species. Here we investigated the effect of salicylate on the susceptibility of Mycobacterium tuberculosis to a range of antituberculosis (anti-TB) drugs. In the presence of salicylate, the killing effects of isoniazid (INH), rifampin (RMP), ethambutol (EMB), streptomycin (STR), and p-aminosalicylate (PAS) were reduced, as s...
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BACKGROUND Sudan is a large country with a diverse population and history of civil conflict. Poverty levels are high with a gross national income per capita of less than two thousand dollars. The country has a high burden of tuberculosis (TB) with an estimated 50,000 incident cases during 2009, when the estimated prevalence was 209 cases per 100,000 of the population. Few studies have been unde...
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We noted with interest the paper by Forgacs et al. (2) reporting on a case of tuberculosis with an apparent response to treatment with trimethoprim-sulfamethoxazole (TMP-SMX) and the subsequent in vitro studies indicating that the majority of Mycobacterium tuberculosis strains may be susceptible to TMP-SMX. As the Forgacs paper implied that it is the sulfonamide component of TMP-SMX that has an...
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ژورنال
عنوان ژورنال: Clinical Microbiology: Open Access
سال: 2012
ISSN: 2327-5073
DOI: 10.4172/2327-5073.1000e109